Guide to Cartridge Purification of Oligonucleotides with DuPont™ AmberChrom™ Resins

This guide describes a quick and effective method for oligonucleotide purification and detritylation using a cartridge purification process. This method is useful for benchtop research scientists and small-scale oligonucleotide manufacturers who seek a crude but fast bench-scale preparative step that combines detritylation and purification in a single step.

Guide to Cartridge Purification of Oligonucleotides with DuPontb" AmberChromb" Resins